MEN Media said it needed to reduce its costs substantially to become more sustainable as a business, adding that redundancies were unavoidable in the current economic climate.
MEN Media is looking to make 41 of the channel's 74 staff redundant and said it could not rule out compulsory redundancies. The move follows an announcement last month that GMG Regional was to make 150 staff redundant at MEN Media.
From June, Channel M will focus on its three-hour early evening Greater Manchester news and information show from 4pm to 7pm, and on general sports programming.
Mark Dodson, chief executive of GMG Regional Media, said GMG continued to believe there would be a successful future for local TV in the UK. He added that the company reserved the option to restore aspects of the schedule should economic circumstances improve.
MEN Media will continue to discuss the future of Channel M with the Government, regulators and other industry players.
MEN Media's Channel M to cut jobs and reduce hours

LONDON - Guardian Media Group-owned MEN Media is to cut the broadcasting hours of its regional TV station Channel M and make 41 staff redundant.